

Leukaemia
Leukaemia is a cancer of the blood and bone marrow, characterized by the uncontrolled production of abnormal blood cells, usually white blood cells. These abnormal cells crowd out healthy blood cells, impairing the body’s ability to function properly.


Types of Leukaemia
Leukaemia is categorized based on how quickly it progresses (acute or chronic) and the type of blood cell affected (lymphocytic or myeloid):
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Acute Lymphocytic Leukaemia (ALL):
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Rapid onset and progression.
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Affects lymphoid cells, which are a type of white blood cell.
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Most common in children but can also occur in adults.
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Acute Myeloid Leukaemia (AML):
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Rapid onset and progression.
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Affects myeloid cells, which develop into different blood cells, including red blood cells, white blood cells, and platelets.
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More common in adults.
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Chronic Lymphocytic Leukaemia (CLL):
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Slow progression.
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Affects lymphocytes and is more common in older adults.
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Often diagnosed during routine blood tests before symptoms appear.
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Chronic Myeloid Leukaemia (CML):
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Slow progression.
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Affects myeloid cells.
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Associated with the Philadelphia chromosome, a specific genetic mutation.
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Symptoms-Diagnosis
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Fatigue and weakness.
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Frequent infections.
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Easy bruising or bleeding.
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Fever or chills.
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Swollen lymph nodes, spleen, or liver.
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Bone or joint pain.
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Night sweats.
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Weight loss.
Leukaemia is diagnosed using various tests, including:
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Blood Tests: Abnormal levels of white blood cells, red blood cells, or platelets.
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Bone Marrow Biopsy: Examines bone marrow samples for abnormal cells.
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Genetic Tests: Identify specific mutations associated with different types of leukaemia.
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Imaging Tests: CT scans or ultrasounds to detect the spread of leukaemia.



Treatment of Leukaemia
Treatment options depend on the type of leukaemia, its progression, and the patient’s overall health:
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Chemotherapy: The primary treatment for most leukaemia, using drugs to kill cancer cells.
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Radiation Therapy: Uses high-energy radiation to target and destroy leukaemia cells.
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Targeted Therapy: Drugs that specifically target genetic mutations in leukaemia cells.
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Immunotherapy: Stimulates the immune system to attack cancer cells.
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Stem Cell Transplant: Replaces diseased bone marrow with healthy stem cells to regenerate normal blood cells.
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Clinical Trials: Experimental therapies that may provide new treatment options.
Early diagnosis and appropriate treatment are crucial for managing leukaemia and improving outcomes. The prognosis varies widely depending on the type of leukaemia and the patient’s response to treatment.